Source: | Mouse | Gene Id: | 27123 |
Isotype: | / | Swiss Prot: | Q9UBU2 |
purity: | Affinity purification |
Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 28, 32 kDa |
Recommended Dilutions | |
Immunogen | DKK2 (ADR828891, 1 aa ~ 259 aa) full-length human protein |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | DKK-2 |
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