Source: | Mouse | Gene Id: | 9794 |
Isotype: | / | Swiss Prot: | Q92585 |
purity: | Affinity purification |
Background: |
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 130 kDa |
Recommended Dilutions | |
Immunogen | MAML1 (NP_055572, 655 aa ~ 754 aa) partial recombinant protein with GST tag |
Storage | Store at -20°C or lower in 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | KIAA0200, Mam-1, Mam1 |
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