
| Source: | Rabbit | Gene Id: | 51561 | 
| Isotype: | IgG | Swiss Prot: | Q9NPF7 | 
| purity: | Purified by Protein A. | 
| Background: | 
| Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB FC IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    FC 1:20-1:100 
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human IL-23 | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | P19, SGRF, IL-23, IL-23A, IL23P19, Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19, IL23A, UNQ2498/PRO5798 | 
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