Source: | Rabbit | Gene Id: | 6507 |
Isotype: | / | Swiss Prot: | P43003 |
purity: | Affinity purification |
Background: |
Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 59.50 kDa |
Recommended Dilutions | |
Immunogen | SLC1A3 (NP_0041632, 1 aa ~ 542 aa) full-length human protein |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | EA6, EAAT1, FLJ25094, GLAST, GLAST1 |
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