Source: | Rabbit | Gene Id: | 6237 |
Isotype: | / | Swiss Prot: | P10301 |
purity: | Affinity purification |
Background: |
R-Ras, a member of the small GTPase family, is homologous to H-, K- and N-Ras, but does not activate MAP kinase pathways and is only weakly oncogenic. Instead, R-Ras is engaged in integrin activation. The effector loop and the carboxy-terminal proline-rich and prenylation sites of R-Ras are critical for integrin activation. Phosphorylation by EphB2 receptor tyrosine kinase and Src at Tyr66 of R-Ras suppresses integrin activity. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 23.50 kDa |
Recommended Dilutions | |
Immunogen | RRAS (NP_0062611, 1 aa ~ 218 aa) full-length human protein |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | / |
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