| Source: | Rabbit | Gene Id: | 5106 |
| Isotype: | / | Swiss Prot: | Q16822 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 70.7 kDa |
| Recommended Dilutions | |
| Immunogen | PCK2 (AAH014541, 1 aa ~ 640 aa) full-length human protein |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | PEPCK, PEPCK-M, PEPCK2 |
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