PAK2 Mouse Polyclonal Antibody
No Size Price Availability  
AMP5062-11 50ul 1500.00 In Stock
AMP5062-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 5062
Isotype: / Swiss Prot: Q13177
purity: Affinity purification
Background:
PAK2, also named as PAK65, PAKgamma, p58, PAK-2p27, PAK-2p24 and C-t-PAK2, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. PAK2 acts on a variety of targets. PAK2 catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. PAK2 phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway. Cleaved PAK-2p34 seems to have a higher activity than the CDC42-activated form. The antibody has no cross reaction to PAK1 and PAK3.
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 57.64 kDa
Recommended Dilutions
Immunogen PAK2 (NP_0025682, 1 aa ~ 524 aa) full-length human protein
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym PAK65, PAKgamma
This product is for research use only, not for diagnostic or therapeutic use!

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