| No | Size | Price | Availability | |
| AMP1107-11 | 50ul | 1500.00 | In Stock |  |
| AMP1107-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 1107 |
| Isotype: | / | Swiss Prot: | Q12873-3 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
| Reactivity | Human |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 260 kDa |
| Recommended Dilutions | |
| Immunogen | CHD3 (NP_001005273, 1654 a.a. ~ 1741 a.a) partial recombinant protein with GST tag |
| Storage | Store at -20°C or lower in 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Mi-2a, Mi2-ALPHA, ZFH |
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