| No | Size | Price | Availability | |
| ARP324-11 | 50ul | 1500.00 | In Stock |  |
| ARP324-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 324 |
| Isotype: | / | Swiss Prot: | P25054 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 160 kDa truncated APC in SW480 cells 310 kDa full-length APC |
| Recommended Dilutions | |
| Immunogen | APC (AAI115921, 1 aa ~ 2843 aa) full-length human protein |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | BTPS2, DP2, DP2.5, DP3, GS |
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