| No | Size | Price | Availability | |
| ARP4437-62 | 50ul | 1500.00 | In Stock |  |
| ARP4437-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4437 |
| Isotype: | IgG | Swiss Prot: | P20585 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |
| Reactivity | Human |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 127 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human MSH3 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5458% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DUP, MRP1 |
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