Source: | Rabbit | Gene Id: | 353 |
Isotype: | IgG | Swiss Prot: | P07741 |
purity: | Affinity purification |
Background: |
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 19 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human APRT |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5591% glycerol. Avoid freeze/thaw cycles. |
Synonym | AMP, APRTD |
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