Source: | Rabbit | Gene Id: | 2674 |
Isotype: | IgG | Swiss Prot: | P56159 |
purity: | Affinity purification |
Background: |
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 51 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human GFRA1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6012% glycerol. Avoid freeze/thaw cycles. |
Synonym | GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1 |
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