
| Source: | Rabbit | Gene Id: | 3615 |
| Isotype: | IgG | Swiss Prot: | P12268 |
| purity: | Affinity purification |
| Background: |
| This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 55 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human IMPDH2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6064% glycerol. Avoid freeze/thaw cycles. |
| Synonym | IMPD2, IMPDH-II |
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