Source: | Rabbit | Gene Id: | 2691 |
Isotype: | IgG | Swiss Prot: | P01286 |
purity: | Affinity purification |
Background: |
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 12 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
IF 1:50-1:200
|
Immunogen | Rabbit IgG |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5463% glycerol. Avoid freeze/thaw cycles. |
Synonym | GHRH |
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