Source: | Rabbit | Gene Id: | 1788 |
Isotype: | IgG | Swiss Prot: | Q9Y6K1 |
purity: | Affinity purification |
Background: |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 78 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human DNMT3A |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6247% glycerol. Avoid freeze/thaw cycles. |
Synonym | DNMT3A2, M.HsaIIIA |
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