Source: | Rabbit | Gene Id: | 8487 |
Isotype: | IgG | Swiss Prot: | O14893 |
purity: | Affinity purification |
Background: |
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 32 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide of humanGEMIN2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5763% glycerol. Avoid freeze/thaw cycles. |
Synonym | SIP1, SIP1-delta |
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