RAMP2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP10266-61 50ul 1500.00 In Stock
ARP10266-61 100ul 2000.00 In Stock
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Source: Gene Id: 10266
Isotype: Swiss Prot: O60895
purity:
Background:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 20 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A synthetic peptide of human RAMP2
Storage
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

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