Source: | Rabbit | Gene Id: | 3651 |
Isotype: | IgG | Swiss Prot: | P52945 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 31 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of humanPDX1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5756% glycerol. Avoid freeze/thaw cycles. |
Synonym | GSF,IPF1,IUF1,IDX-1,MODY4,PDX-1,STF-1 |
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