Source: | Rabbit | Gene Id: | 50855 |
Isotype: | IgG | Swiss Prot: | Q9NPB6 |
purity: | Affinity purification |
Background: |
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 37 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of human PRKC |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5828% glycerol. Avoid freeze/thaw cycles. |
Synonym | PAR6,PAR6C,TAX40,PAR-6A,TIP-40,PAR6alpha |
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