Source: | Rabbit | Gene Id: | 4363 |
Isotype: | IgG | Swiss Prot: | P33527 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 173 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
Immunogen | A synthetic peptide of human ABCC1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5562% glycerol. Avoid freeze/thaw cycles. |
Synonym | MRP, ABCC, GS-X, MRP1, ABC29 |
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