Source: | Rabbit | Gene Id: | 3817 |
Isotype: | IgG | Swiss Prot: | P20151 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 29 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:100-1:200
|
Immunogen | A synthetic peptide of human KLK2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5727% glycerol. Avoid freeze/thaw cycles. |
Synonym | hK2, hGK-1, KLK2A2 |
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