| No | Size | Price | Availability | |
| ARP3814-61 | 50ul | 1500.00 | In Stock |  |
| ARP3814-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3814 |
| Isotype: | IgG | Swiss Prot: | Q15726 |
| purity: | Affinity purification |
| Background: |
| This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 15 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:25-1:100
|
| Immunogen | A synthetic peptide of human KISS1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5526% glycerol. Avoid freeze/thaw cycles. |
| Synonym | HH13, KiSS-1 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
