Source: | Rabbit | Gene Id: | 3757 |
Isotype: | IgG | Swiss Prot: | Q12809 |
purity: | Affinity purification |
Background: |
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide of human KCNH2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6306% glycerol. Avoid freeze/thaw cycles. |
Synonym | ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.