KCNH2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3757-61 50ul 1500.00 In Stock
ARP3757-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3757
Isotype: IgG Swiss Prot: Q12809
purity: Affinity purification
Background:
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 90 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A synthetic peptide of human KCNH2
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 6306% glycerol. Avoid freeze/thaw cycles.
Synonym ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1
This product is for research use only, not for diagnostic or therapeutic use!

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