
| Source: | Rabbit | Gene Id: | 1910 |
| Isotype: | IgG | Swiss Prot: | P24530 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide of human EDNRB |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 5997% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ETB,ET-B,ETBR,ETRB,HSCR,WS4A,ABCDS,ET-BR,HSCR2 |
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