Source: | Rabbit | Gene Id: | 50674 |
Isotype: | IgG | Swiss Prot: | Q9Y4Z2 |
purity: | Affinity purification |
Background: |
Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix (bHLH) transcription factors involved in the determination of neural precursor cells in the neuroectoderm. The pancreas and brain the major splicing isoform does not code for a protein. Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 23 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
Immunogen | A recombinant protein of human NEUROG3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ngn3, Atoh5, NGN-3, Math4B, bHLHa7 |
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