
| Source: | Rabbit | Gene Id: | 333 |
| Isotype: | IgG | Swiss Prot: | P51693 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 72 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
|
| Immunogen | A recombinant protein of human APLP1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | APLP |
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