Source: | Rabbit | Gene Id: | 84868 |
Isotype: | IgG | Swiss Prot: | Q8TDQ0 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Reactivity | Human |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 33 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human HAVCR2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | TIM3, KIM-3, TIMD3, Tim-3, TIMD-3, HAVcr-2 |
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