| No | Size | Price | Availability | |
| ARP2775-61 | 50ul | 1500.00 | In Stock |  |
| ARP2775-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2775 |
| Isotype: | IgG | Swiss Prot: | P09471 |
| purity: | Affinity purification |
| Background: |
| Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 40 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human GNAO1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GNAO, EIEE17, G-ALPHA-o |
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