IQGAP3 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP11861-01 50ul 1500.00 In Stock
YRP11861-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id:
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
IQGAP3 is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human IQGAP3
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym IQ mot containing GTPase activating protein 3, IQGA3_HUMAN, IQGAP 3 , IQGAP3, MGC10170, MGC10831, MGC1947 antibodyOTTHUMP00000031854 , OTTHUMP00000031855, Ras GTPase activating like protein IQGAP3, Ras GTPase-activating-like protein IQGAP3.
This product is for research use only, not for diagnostic or therapeutic use!

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