
| Source: | Rabbit | Gene Id: | 121504 | 
| Isotype: | IgG | Swiss Prot: | P62805 | 
| purity: | Affinity purification | 
| Background: | 
| Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. | 
| Reactivity | Human, Mouse, Rat, Other(Wide Range) | 
| Tested applications | WB IF IP ChIP | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 11 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IF 1:50-1:200 ChIP 1:50-1:200 | 
| Immunogen | A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4 | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | H4, H4/n, H4F2, H4FN, FO108, HIST2H4 | 
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