| No | Size | Price | Availability | |
| ARP5663-62 | 50ul | 1500.00 | In Stock |  |
| ARP5663-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5663 |
| Isotype: | IgG | Swiss Prot: | P49768 |
| purity: | Affinity purification |
| Background: |
| Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer disease, probably due to presenilin's associated γ-secretase activity for amyloid-β protein processing (1,2). Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (~20, 22, 23 kDa) fragments (CTF) (2,3). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 53 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human PSEN1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PSEN1, AD3, FAD, PS-1, PS1, S182 |
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