
| Source: | Rabbit | Gene Id: | 5378 | 
| Isotype: | IgG | Swiss Prot: | P54277 | 
| purity: | Affinity purification | 
| Background: | 
| PMS1 belongs to the DNA mismatch repair mutL/hexB family. It is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other proteins involved in the HNPCC phenotype, which is also known as Lynch syndrome (1). | 
| Reactivity | Human, Rat | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 106 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:200 | 
| Immunogen | A recombinant protein of human PMS1 | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1,PMS1 | 
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