Source: | Rabbit | Gene Id: | 836 |
Isotype: | IgG | Swiss Prot: | P42574 |
purity: | Affinity purification |
Background: |
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2). |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IP |
Clonality | Polyclonal Antibody |
Calculated MW | 17 kDa;19 kDa;35 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptideof human CASP3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CASP3,CPP32,CPP32B,SCA-1,Caspase-3,APOPAIN |
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