Source: | Rabbit | Gene Id: | 7517 |
Isotype: | IgG | Swiss Prot: | O43542 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 38 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human XRCC3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CMM6 |
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