
| Source: | Rabbit | Gene Id: | 3428 | 
| Isotype: | IgG | Swiss Prot: | Q16666 | 
| purity: | Affinity purification | 
| Background: | 
| This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | 
| Reactivity | Human | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 88 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:200 | 
| Immunogen | A recombinant protein of human IFI16 | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | PYHIN2, IFNGIP1 | 
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