
| Source: | Rabbit | Gene Id: | 1647 | 
| Isotype: | IgG | Swiss Prot: | P24522 | 
| purity: | Affinity purification | 
| Background: | 
| This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 18 kDa | 
| Recommended Dilutions | WB 1:500-1:2000 IHC 1:50-1:200 | 
| Immunogen | A recombinant protein of human GADD45A | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | DDIT1, GADD45 | 
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