Source: | Rabbit | Gene Id: | 4155 |
Isotype: | IgG | Swiss Prot: | P02686 |
purity: | Affinity purification |
Background: |
MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. This is a rabbit polyclonal antibody raised against the full-length of human MBP,and is capable of recognizing multiple isoforms of MBP. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 33 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human MBP |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC99675 |
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