| No | Size | Price | Availability | |
| ARP8856-62 | 50ul | 1500.00 | In Stock |  |
| ARP8856-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8856 |
| Isotype: | IgG | Swiss Prot: | O75469 |
| purity: | Affinity purification |
| Background: |
| This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human NR1I2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq |
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