| No | Size | Price | Availability | |
| ARP7166-61 | 50ul | 1500.00 | In Stock |  |
| ARP7166-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7166 |
| Isotype: | IgG | Swiss Prot: | P17752 |
| purity: | Affinity purification |
| Background: |
| Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin (1) by converting tryptophan to 5-hydroxy-L-tryptophan (2). Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system (3). Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin (4). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 55 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human TPH1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | TPH1,MGC119994,TPRH,TRPH,Tryptophan 5-hydroxylase 1 |
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