BMP4 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP652-62 50ul 1500.00 In Stock
ARP652-62 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 652
Isotype: IgG Swiss Prot: P12644
purity: Affinity purification
Background:
Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs belongs to the TGF-β superfamily, playing many diverse functions during development (3). BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4).
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 47 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
Immunogen A recombinant protein of human BMP4
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym BMP2B, BMP2B1, MCOPS6, ZYME
This product is for research use only, not for diagnostic or therapeutic use!

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