Source: | Rabbit | Gene Id: | 1280 |
Isotype: | IgG | Swiss Prot: | P02458 |
purity: | Affinity purification |
Background: |
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humorof the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familialosteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, andspondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium bindingprotein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are twotranscripts identified for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 142 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
Immunogen | A recombinant protein of human COL2A1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ANFH,AOM,COL11A3,MGC131516,SEDC |
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