| No | Size | Price | Availability | |
| ARP11186-61 | 50ul | 1500.00 | In Stock |  |
| ARP11186-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 11186 |
| Isotype: | IgG | Swiss Prot: | Q9NS23 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 39 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human RASSF1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 123F2, RDA32, NORE2A, RASSF1A, REH3P21 |
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