| No | Size | Price | Availability | |
| ARP6240-61 | 50ul | 1500.00 | In Stock |  |
| ARP6240-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6240 |
| Isotype: | IgG | Swiss Prot: | P23921 |
| purity: | Affinity purification |
| Background: |
| Ribonucleotide reductase catalyzes the rate-limiting step in the synthesis of deoxynucleotide triphosphates (dNTPs). The regulatory M1 subunit (RRM1) is present throughout the cell division cycle, but downregulated in quiescent cells (1). Research studies have demonstrated that RRM1 is involved in carcinogenesis and tumor progression, and its expression is correlated with resistance to chemotherapy in non-small cell lung cancer (2-4). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 90 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human RRM1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | RRM1,R1,RIR1,RR1 |
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