| No | Size | Price | Availability | |
| ARP3313-62 | 50ul | 1500.00 | In Stock |  |
| ARP3313-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3313 |
| Isotype: | IgG | Swiss Prot: | P38646 |
| purity: | Affinity purification |
| Background: |
| Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible (1,2). This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria (3). Grp75 inactivates the tumor suppressor p53 (4). Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (5). Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (6). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 74 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human HSPA9 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | HSPA9,CSA,GRP75,HSPA9B,MGC4500,MOT,MOT2,MTHSP75,PBP74,mot-2 |
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