| No | Size | Price | Availability | |
| ARP581-63 | 50ul | 1500.00 | In Stock |  |
| ARP581-63 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 581 |
| Isotype: | IgG | Swiss Prot: | Q07812 |
| purity: | Affinity purification |
| Background: |
| Bax is a key component for cellular induced apoptosis through mitochondrial stress (1). Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane (2). Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis (3,4). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 21 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A recombinant protein of human Bax |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BAX,BCL2L4 |
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