Source: | Rabbit | Gene Id: | 1909 |
Isotype: | IgG | Swiss Prot: | P25101 |
purity: | Affinity purification |
Background: |
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
Reactivity | Human, Mouse |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 48 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | endothelin A receptor, endothelin receptor type A, endothelin-1 receptor, ET-A, ETA, ETA-R, ETRA, G protein-coupled receptor |
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