Source: | Rabbit | Gene Id: | 5734 |
Isotype: | IgG | Swiss Prot: | P35408 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008] |
Reactivity | Human |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 55 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Prostaglandin E2 receptor EP4 subtype, PGE receptor, EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2 |
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