Source: | Rabbit | Gene Id: | 1238 |
Isotype: | IgG | Swiss Prot: | O00590 |
purity: | Affinity purification |
Background: |
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 34 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Chemokine-binding protein 2, Chemokine-binding protein D6, C-C chemokine receptor D6, Chemokine receptor CCR-9, Chemokine receptor CCR-10, CCBP2, CCR10, CMKBR9 |
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