Source: | Rabbit | Gene Id: | 1509 |
Isotype: | IgG | Swiss Prot: | P07339 |
purity: | Affinity purification |
Background: |
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 45 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CATD, Cathepsin D, Cathepsin D heavy chain, Cathepsin D light chain, ceroid-lipofuscinosis, neuronal 10, CLN10, CPSD, CTSD, lysosomal aspartyl peptidase, lysosomal aspartyl protease, MGC2311 |
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