PKN1 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5585-61 50ul 1500.00 In Stock
ARP5585-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5585
Isotype: IgG Swiss Prot: Q16512
purity: Affinity purification
Background:
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 104 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym DBK, MGC46204, PAK1, PKN, PKN-ALPHA, PKN1, PRK1, PRKCL1, Protein kinase C-like 1, Protein kinase C-like PKN, protein kinase C-related kinase 1, protein kinase N1, Protein kinase PKN-alpha, Protein-kinase C-related kinase 1, serine-threonine kinase N, Seri
This product is for research use only, not for diagnostic or therapeutic use!

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